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2'O methyl phosphorothioate (2OMePS) AOs induced functional amount of dystrophin expression in tibialis anterior (TA) muscles by local injection and further showed systemic effect in body-wide muscles [4], [5].
This is because there is a greater a priori rationale that a CNV should influence disease risk, compared with a SNP (due to the larger, and clearly functional amount of DNA involved) (71).
Cells were transfected with either P-1257 or P-scr peptides and through a dose-response experiment we established the functional amount of P-1257 required to inhibit the level of Akt phosphorylation in each cell line, (Supplementary Figure S1).
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Taking advantage of the direct cellular visualization of IFNβ production we were able to show that the spleen acts as the major dwelling place of IFNβ producing cells with a small subpopulation of cells (∼105 per spleen) being sufficient to provide this cytokine in biologically functional amounts.
Functional constraint (amount of intolerance towards nucleotide substitution) within the viral genome can be estimated by the rate of nonsynonymous and synonymous substitutions.
Furthermore, we accounted for functional level, amount of time in hospital, and living in a nursing facility, all of which are measures of disease severity.
Similarly for humans, our method was able to predict 895 out of 914 functional MTIs, amounting to a recall value of 97.9 %.
Secondary outcome measures will include Foot and Ankle Ability Measure, Patient Specific Functional Scale and amount of activity in the previous week.
Moreover in comparison between the two functional groups, the amount of ZnO material loaded on the surface of CNTs with COOH functional group is relatively more than that of OH functionalized CNTs.
We specified a maximal model with "Taxonomic Richness", "Functional Richness", the amount of available "Substratum" and all possible interactions as fixed effects.
The relationship between functional E-cadherin amount, P and exogenous calcium thus closely mirrors the relationship described by [ 21] between binding activity and calcium concentration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com