At those loci, we identify candidate genes which, when rendered non-functional, alter those very demographic properties, and in turn, we identify candidate coding or regulatory variants that alter protein structure or gene expression, respectively, being prospective contributors to the variation in phenotype.
In both studies, post-loss changes in the relationship between species' traits and their functional contributions alter ecosystem function more than nonrandom loss of species with particular traits.
Aging is invariably associated with alterations of the hematopoietic stem cell (HSC) compartment, including loss of functional capacity, altered clonal composition, and changes in lineage contribution.
These associations give strong support to the notion that we are able to identify functional elements altered by genetic variation.
The same functional parameters altered by kindling and prenatal exposure to ethanol are also modified during the normal development of the brain.
The base of this therapeutic method is to introduce a gene encoding a functional protein altering the expression of an endogenous gene or possessing the capacity to cure or prevent the progression of a disease [1 3].
According to the authors, the viability of the examined cancer cell lines was dependent upon both the concentration of TiO2 NPs in the examined cells and the type of functional group altering the surface properties of TiO2 NPs.
They may therefore be indirect targets or possess functional but altered PHO boxes.
To extrapolate major cellular functional networks altered in HU-treated NSCs, we performed IPA pathway analysis.
To analyze this in more detail, we tested if the functional groups altered in PDX models were similarly altered in metastases (compared with primary tumors).
Functional limitations, altered cardiac autonomic activity, and psychological distress are known disorders in patients with liver cirrhosis, relating to increased morbidity and mortality.
