Our results also indicate that C2Analyzer may help elucidate the functions of some functionally-unidentified miRNAs.
There is the possibility that critical partners that regulate Slo3 function remain unidentified.
In terms of RNase activities, hRNases1-to-8 have obvious catalytic activities; however, such function is unidentified in hRNases9-to-13 and remains to be elucidated.
In this context it would be of interest to find out whether Δ9- or Δ11-desaturases (or another desaturase function yet unidentified) underlie the double-bond formation in the biosynthesis of (Z -4-hepten-2-ol and (Z -4-hepten-2-ol(and their corresponding ketones) as observed in Eriocraniidae moths and in Trichoptera.
Interestingly, the GO category "molecular function unknown" ranked high for the Δ mig1 mutant, suggesting that many genes affected by the deletion of MIG1 still have an unidentified function.
Unlike humans, mice and other lower vertebrates have the TLR11 subfamily, which includes TLR12 and TLR13, whose ligands and functions are unidentified [2].
Nevertheless, inhibition of PGRN endocytosis might influence PGRN's intracellular functions or unidentified intracellular signaling pathways, especially in cells that rely on its uptake from the extracellular space or neighbor cells.
In addition, a cooperative interaction between ispd, fktn and fkrp in glycosylating α-dystroglycan was identified in zebrafish, demonstrating that functions previously unidentified in vertebrates can be elucidated in zebrafish (Roscioli et al., 2012).
Overall, these 16 non-classified hypervirulent PHI-base mutations may represent species-specific biological functions and/or unidentified unifying themes which will become apparent as the documentation of the hypervirulent phenotype expands.
However, other SERK genes in M. truncatula and other legumes are largely unidentified and their functions unknown.
