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The cubature formula not only generates unequal-weighted collocation samples, which has much faster convergent rate, but also provides the target variance of the performance function to terminate the iterative process.
Given that negative feedback mechanisms and their relative strengths are major determinants of the oscillatory dynamics, they do not simply function to terminate signaling.
The computability of a function does not require termination for an input value on which that function is not defined, so it is not necessary for a Turing machine computing that function to terminate for every input.
Importantly, the InsP3-Kinase (IP3KB), the isoform that inactivates the InsP3 by phosphorylating it, was also reported to be located in the nucleoplasmic reticulum, where it may function to terminate the InsP3 mediated Ca2+ signal [ 49].
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The ESCRT machinery plays a fundamental role in the turnover of membrane bound cargo and functions to terminate receptor signaling in multiple contexts [5].
AMPKα1 is thus a dynamic sensor for glucose uptake and functions to terminate mTORC1 activity under conditions of energy stress in CTLs.
Thus TEFt functions bi-directionally to terminate SUT650 (BK), the sense transcript from p TEF, expressing the kanamycin resistance (KanMX) transcript (K), and the sense transcript (AK) initiated at the HMS2 promoter and terminating at TEFt. p TEF is a well-characterised (Steiner and Philippsen, 1994) strong bi-directional promoter and produces an antisense transcript (E) extending into p HMS2.
This similarity to translation termination complexes suggested that Dom34 and Hbs1 function at elongation stalls to terminate translation, which has been demonstrated using reconstituted systems from both yeast and mammals (Shoemaker et al. 2010; Pisareva et al. 2011).
The best-characterized function of yeast Sen1 is to terminate RNAPII transcripts acting in a complex with two RNA-binding proteins, Nrd1 and Nab3.
However, to terminate the signaling function of (mono- ubiquitination a cell can choose between either de-ubiquitination or poly-ubiquitination.
In the more superficial parts of the dermis, minute lymph vessels that appear to terminate in blind sacs function as affluents of a superficial lymphatic net that in turn opens into vessels that become progressively larger in the deeper portions of the dermis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com