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In their mature forms, siRNA and miRNAs function to regulate gene expression through different mechanisms (Bartel, 2004).
The structure and properties of the PG-1 dominant-negative mutation demonstrate a mechanism for manipulating Myb gene structure that can provide useful insight into the mechanisms by which MYB transcription factors function to regulate gene expression in plants.
In general, these molecules function to regulate gene expression at the transcriptional and post-transcriptional level.
How BAF complexes function to regulate gene expression within these cell lineages is still poorly understood.
miRNAs are small (20 22 nt) non-coding RNAs which function to regulate gene expression in the cell.
Enhancers are components of the genome that function to regulate gene expression and are critical for proper cellular differentiation.
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The androgen receptor (AR), a member of the nuclear receptor superfamily, functions to regulate gene expression in response to androgens such as testosterone (T) and dihydrotestosterone (DHT).
Furthermore, we also isolated, sequenced and verified some fragments that are differentially methylated among different tissues, which may be useful for further investigations into how methylation functions to regulate gene expression.
In addition, the Nuclear Factor-κB (NFκB) transcription factor complex was identified as a major node and members of this family are known to interact with HMGA1 and form a higher order transcriptional complex or enhanceosome that functions to regulate gene expression of specific transcriptional targets, such as IFNβ [ 16, 48- 53].
CBP is a general transcriptional coactivator that functions to regulate gene expression through interaction with various transcription factors, including CREB (Giordano and Avantaggiati 1999), Elk 1 (Janknecht and Nordheim 1996), c-Jun (Giordano and Avantaggiati 1999), and TBP (TATA box binding protein) (Goodman and Smolik 2000).
Signal molecules implicated in cell cell communication are known as auto-inducers and/or QSM and their function is to regulate gene expression in other cells of the community to control bacterial responses (Nealson et al. 1970).
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