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The patients described in the present investigation were participating in a large-scale prospective study examining subjective and objective aspects of locomotor function before and after TKA (results on objective changes in function to be reported elsewhere).
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Although snoRNA host genes with ribosome-translation-related functions were the first to be reported, some snoRNAs are also hosted by non-ribosome or non-translation-related genes.
The impact of untreated depression and anxiety on the ability to function is reported to be equal or greater than that of other common health problems such as heart disease or arthritis [ 15].
In an European study that followed 152 patients with RE for 10 years and compared the QOL assessed using the SF-36 between RE patients and the general population, physical function and social function were reported to be significantly lower in patients with RE[ 12].
Some proteins connected to filopodium formation or function have been reported to be related to cancer progression.
The reduced muscle mitochondrial function has been reported to lead to a decrease in muscle mass and the development of obesity and diabetes15, 16.
As a result, hundreds of genes relevant to various functions have been reported to play a role in the process [ 21].
1, 2 Kidney function has been reported to be abnormal in up to 30% of HIV-infected patients.
The vasodilator response to exogenous NO reflects vascular smooth muscle function and is reported to be impaired independently of endothelial dysfunction in subjects at risk for atherosclerosis [ 26].
Indeed, the amygdala is important for emotional processing and its functional abnormalities are associated with depression [42], [43], [44], and frontal cortical dopamine function has been reported to be involved in depression [45], [46], [47].
Balance function has been reported to be worse in ADHD children than in their normal peers.
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