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All MS and MS/MS spectra were acquired with the Q2-pulsing function switched on, and optimized for enhanced transmission of ions in the MS (m/ z 400 1000) and MS/MS (m/ z 75 1300) mass ranges.
In fact, loss of HDAC function switched the response to TGF-β from one of repression to one of activation (in agreement with previous studies of the osteocalcin promoter).
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But when an electron absorbs light, its wave function switches to a dumb-bell shape that pushes against the poles of the bubble but not against its equator.
* Environmentally friendly auto-standby function switches the units to standby mode when no input or usage is detected for over 60 minutes.
At an inflection point, a function switches from being a convex function to being a concave function or vice versa.
Two additional models are included in the performed analysis: the "classical" SIR model and a SIR model assuming time-dependent transmission rate, which is considered to be a step function switching between two values at a given time.
Additional conditional in vivo loss-of-function data will be required to clarify whether β-catenin function switches from CM proliferation-promoting in the embryo to hypertrophy-promoting in the adult.
One observation that appears to conflict with the hypothesis that KGB-1's function switches to detrimental in adulthood is that lifespan of kgb-1 mutants is often shorter than that of wild-type animals (Fig. 2G).
We demonstrate a dose-dependent effect of Fgf10 on H-NH axons, its attractive function switching to repellant activity at high concentrations, suggesting a mechanism for the stalling of axons as they reach the NH.
A possible explanation for the more severe phenotype of the missense mutations is that these mutations result in a gain of function, switching the SMARCA2/4 proteins to a constantly "on" state.
The OPCs may also be able to sense the amount of PDGF-A by the "rheostat-like" PDGFRα function, switching downstream signaling from the PI3K pathway to PLC–γ under higher PDGF-A concentration [41].
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