Sentence examples for function studies as from inspiring English sources

Thus, iVPR cells provide a convenient platform for gene function studies as well as high-throughput screens in hPSCs.

Thus, silkworm-based BmNPV system provides a reliable large-scale protein production platform for structural and function studies as well as drug discovery applications implementing essential posttranslational modifications.

For this purpose, we are performing gain and loss of function studies as well as FRET experiments to determine spatial lipid protein proximity.

However, functional analyses such as loss-of-function and/or gain-of-function studies as well as localization analysis are needed to further analyze its potential functions.

iCRISPR enabled rapid and highly efficient generation of biallelic knockout hPSCs for loss-of-function studies, as well as homozygous knockin hPSCs with specific nucleotide alterations for precise modeling of disease conditions.

This is especially true for structure-function studies, as well as for understanding the effects of mutations found in humans.

This review discusses recent advances in the field, revisits older findings in this context and highlights current developments in structure-function studies as well as methodology that make mycolactone a promising diagnostic biomarker.

Importantly, since shRNAs do not modify the genomic loci of target genes, the system enables transient, reversible gene silencing (Dow et al., 2012; Premsrirut et al., 2011), thereby facilitating genetic loss-of-function studies as well as an assessment of reversible and irreversible phenotypes simply by adding and removing dox from the diet.

There was no difference regarding age, sex, socio-demographic, and anthropometric variables between the participants included in the thyroid function study as compared to the 699 non-participants.

Tier three markers are most likely to be difficult to translate to disease understanding via gene-function studies as they may be in less understood regions of the genome or they may implicate genes in pathways not known to be involved in the disease of interest.

ADAM2 has an ECD tripeptide in the disintegrin domain that was characterized by structure-function studies as important for ADAM2 binding to eggs [24], [25], and also has a sequence similar to the RX6DLPEF motif in ADAM15 that is important in binding ITGA9-ITGB1 [33] (RLAQDECDVTEY in mouse ADAM2, RPSFEECDLPEY in human ADAM2).