Sentence examples for function redundancy from inspiring English sources

The two different expression patterns in different tissues of the 12 duplicated gene pairs suggest functional diversification and possible function redundancy (or gene silencing), respectively.

Potential drug targets are then subjected to high-throughput screening for inhibitors, which often fail at the cellular level in "hit-to-lead" stages of development due to several factors [7], such as gene function redundancy [8].

In soybean roots, the overall similar patterns in promoter activity of the duplicated genes, such as GmPIN1b- 1c, GmPIN2a- 2b, and GmPIN3a- 3b, further suggest their function redundancy.

Function redundancy, signalling via alternative signalling pathways or growth factor receptor crosstalk has shown that the antitumour activity of monotherapeutic regimes are easily subverted.

Two other additional criteria for chimera detection were computed: the tetranucleotide homogeneity score and function redundancy (see Additional file 4: Table S3, draft genome quality sheet; and the supplementary information document).

The two receptors appear to promote distinct TNF-α-induced cellular responses, although both are capable of inducing the nuclear factor-κB (NF-κB) and apoptotic pathways [ 7- 10], providing some evidence of receptor function redundancy.

High functional diversity (i.e., the breadth of species' ecological functions), functional redundancy (i.e., the number of species performing similar functions in the system) and functional vulnerability (i.e., decrease in functional diversity following the loss of species) are critical for sustaining ecosystem function8,11,12.

This could be due to two reasons: (1) the incomplete AtPV42b transcript produced from the coding region preceding the T-DNA insertion site may still function; (2) functional redundancy between AtPV42a and AtPV42b may exist.

Hence, no specific roles for either of these enzymes have been assigned in bone or in cartilage developmental processes and it has been suggested that TG2 and FXIIIA have either a synergistic function or functional redundancy, and that they can in some cases compensate for each other [52], [56], [57].

To search clues for specific functions or functional redundancy of ERK isoforms, we studied protein expression of ERK isoforms in parallel with the evolution of their sequences in all key vertebrate clades.

Additionally, for processes where multiple genes of similar function act synergistically, functional redundancy may make time-consuming characterization of null isolates ineffective.