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Nanofibrous scaffolds have been recently used in the field of tissue engineering because of their nano-size structure which promotes cell attachment, function, proliferation and infiltration.
We hypothesized that early-lactation increased milking frequency, in combination with bovine somatotropin (bST), would improve milk yield in continuously milked (CM) primiparous glands through greater mammary epithelial cell (MEC) function, proliferation, and reduced apoptosis (cell turnover).
Together, these results suggest that the calcium-phosphatidylinositol and cyclic AMP cascades may play an important role in the regulation of cell function, proliferation, and differentiation in endometrial carcinogenesis.
As a step towards the goal of increasing beta-cell function, proliferation or survival, we designed a multi-parameter, high content screening platform that enabled us to screen a library containing 1319 unique natural marine invertebrate extracts.
The pathological and immunohistological study presented here, in which thyroid function, proliferation, and the two involved signalling pathways were completely tested and they explain the gene expression results.
Those histological findings were accompanied by changes in the expression of proteins related to thyroid function, proliferation indices, PKB and MAPkinase pathways.
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It remains largely speculative how different cells execute complex final functions (proliferation, invasion, etc).
Despite their diverse functions, proliferation genes have similar gene expression profiles when analyzed by hierarchical clustering.
Therefore, modulation of Th2 cytokines by IFNLs can profoundly affect B-cell functions (proliferation and antibody production).
Identifying the underlying factors requires single-cell analysis of function and proliferation.
As the islet approaches its mature state, heterogeneity diminishes and beta-cells synchronize function and proliferation.
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