Sentence examples for function on longevity from inspiring English sources

18 To test this we determined the effect of loss of HtrA2 Δ1 function on longevity and stress resistance.

Herein, we have investigated the impact of enhanced proteasome function on organismal longevity and aggregation-related pathologies by employing Caenorhabditis elegans as a model system.

The isolation and characterization of a Drosophila mutant with a defect in the iron-sulfur subunit (sdhB) of complex II was the first study to directly investigate the effects of decreased ETC function on fly longevity [ 32].

We examined the effects of HIF-1 over-expression and of hif-1 loss-of-function mutations on longevity in C. elegans, a powerful genetic system in which adult somatic cells are post-mitotic.

Prior studies did not clearly predict the effects a hif-1 loss-of-function mutation might have on longevity.

It seems logical that if the effect improves brain function it could have an impact on longevity.

While there is a dose-dependent reduction in function, the effect of theobromine on both function and longevity is small relative to the effects of the three other substances that we report on here.

Therefore, normal ETC complex I function is necessary for the full effect of βHB on longevity.

Improvements in the function and longevity of these devices hinges on the advent and application of new material components involved, including TiO2, perovskite, and the hole-transporting material (HTM).

Using tissue-specific drivers and dominant-negative {DN) p53 alleles, a reduction in p53 function in adult neurons was shown to have a beneficial effect on longevity [ 9].

These interventions produced effects on longevity that were fully consistent with the functions and abundances of their products.