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The proportion of patients in clinical remission, CDAI 100 and 70 responders are provided in table 3 and plotted as a function of visits for pooled placebo and each laquinimod dose in figure 2A C.
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The mean change in the EDSS score as a function of visit number is shown in figure 5.
In addition, we have chosen to estimate the predictive accuracy using some simple and intuitively clear measures, i.e. mean squared prediction error (MSPE) as a function of the visit number.
In addition, we have derived a relation to assess the improvement in power as a function of number of visits and correlation between visits.
The GEE approach was used to fit a logistic regression model for pubertal onset at each visit as a function of age at visit, with adjustment for potential confounders and correlation among multiple visits via an autoregressive structure.
For example, a graph of the specificity as a function of the alarm threshold corresponds to a predicted cumulative distribution function of the number of visits on any given day.
When comparing Average vs single visit, we show the expected LOD ratio as a function of the number of visits and the correlation between visits.
Our method implements an empirical Bayes algorithm, 'Shrunken Average (SHAVE)', using regression toward the mean for every individual as a function of their number of visits and the correlation between visits.
The estimators derived below and later in "Ratio with tours estimator (RT-estimator)" section exploit the independence of the tours and the result that expected sum of functions of nodes visited in a tour is proportional to (sum _{u in V} g u)) [4, Lemma 3].
In the first model (A) the probability was only a function of the time of visit (after or before the reform).
The cumulative probability of type-specific HPV detection at visits 1 through 14 was determined as a function of infection categorized at visits 1 and 14 as persistent, newly detected, cleared or absent.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com