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To probe the function of the START domain within HD-Zip transcription factors we chose Arabidopsis GL2 for analysis.
The function of the start codon intron may be to allow the 5' UTR to participate in exon shuffling, so that different genes can exchange regulatory information.
We studied the function of the START domain in the synthetic transcription factor with a mammalian StAR protein that is known to bind cholesterol.
Perhaps the interaction between PCTP and Pax3 is analogous to the function of the START domain in plant HD-Zip transcription factors.
While the previous study examined the function of the START domain in an interacting protein [ 34], here we demonstrate the regulatory role of the START domain as an integral part of the transcription factor.
The function of the START domain in GL2 was dependent on the encoded domain sequence, since replacement with two additional Arabidopsis-derived START domains, namely from Enhanced Disease Resistance 2 (EDR2) [ 25] and from class III HD-Zip member Revoluta (REV) [ 26], were not found to rescue the gl2 mutant phenotype, nor did they display nuclear localization.
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Hence, TOM does not predict unconditional cooperation in PD but, instead, makes it a function of the starting point of play.
We describe the use of the fast Fourier transform (FFT) in the measurement of anisotropy in electrospun scaffolds of gelatin as a function of the starting conditions.
Major differences in the relative abundances were not observed as a function of the starting solution (e.g., organic content) and the IMS trapping time.
Figure 6 shows the results of the sensitivity analysis of the number of cases in group 1 as a function of the starting week of emissions (assuming emission profile conYear and a threshold wind velocity of 2 m/s).
We find that when population size varies over time, two important symmetries of the constant population-size scenario are broken: first, the probability of observing soft sweeps becomes a function of the starting time of the sweep and, second, it becomes a function of the strength of selection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com