This involves phrasing an important evolutionary question in two directions, "How well does a more sophisticated model of protein function explain observed evolutionary patterns?" and conversely, "How well do simple evolutionary statistics describing selective constraint (here dN/dS) describe conservation of function or the opportunity for functional shifts in a pathway?".
To be fair, Director Samuels inherited the legacy of Harley Lappin: a rise in violent prison gangs, a prison system saturated with illegal narcotics, and a high recidivism rate that is arguably a function of the lack of educational opportunities and meaningful programs funded by the government.
The surviving hypothesis is the 'security hypothesis' (Farrell et al. 2011a): The crime drops are a function of reduced opportunities, which have been largely brought about by increases in the extent and quality of security, an idea first introduced by Clarke and Newman (2006) and by Van Dijk (2006).
This simplicity means that analysis of the structure and function of the cerebellum offers neuroscientists the opportunity to understand the basic principles of cortical function.
The increasing rate of female entry into international migration in the 2000s is a likely function of shrinking economic opportunities in the home country as well as the growth of gender-segmented labour markets in receiving countries (Table 2).
Although a full understanding of the mechanisms of STING activation requires further studies, new insights into STING function afford the opportunity of designing novel compounds aimed at facilitating vaccine development or new therapies for the treatment of inflammatory disease.
The evolution of the H/E and H3/E*2 parameters as a function of the nanostructure is investigated, and opportunities for their optimization are described.
The sequencing of the human genome, together with the development of high-throughput technologies that measure the function of the genome, have afforded unique opportunities to develop profiles that can distinguish, identify and classify discrete subsets of disease, predict the disease outcome or predict the response to treatment.
Based on the sufficient psychometric properties of the alternative version of the chewing function questionnaire the opportunity exist to assess the target construct over very short periods of time when test-retest effects are expected that would prevent assessment with the same instrument.
This experiment was similar to Experiment I but assessed female longevity as a function of different opportunities to blood-feed.
