Sentence examples for function of the domains from inspiring English sources
T cell epitopes within funtional domains would remain conserved over time as viral mutations useful towards immune escape may disrupt the function of the domains and affect viral fitness unless compensated functionally by multiple co-mutations [49], [50].
To gain further insight into the nature and function of the domains of the human protein X (a pyruvate dehydrogenase complex component also known as the E3-binding protein), we expressed the wild-type as well as two artificially created variants, K37E and S422H, in SV40-immortalized protein X-deficient and E2-deficient human skin fibroblasts.
It has been experimentally determined that the coherence length (atomic pair distribution function) of the domains in glassy carbon tapers off beyond a distance of about 1.2 nm [29].
Since we do not know the function of the domains connecting RpfB and SpsB (DUF348 & G5), it might be more correct to invoke "guilt by association" in the present case.
The structure of LigB-12 has, as expected, an Ig-like fold, but the details of the structure and comparison with other Big proteins provides insight into the function of the domains and their interaction with host proteins.
Therefore, the way we approached the modular structure of the repeats was by looking at the function of the domains involved in adhesion, with only one exception: the AA100 sequence which spans the region located after the repeats, so it was not possible to include it in our description.
Beyond this, we present a novel function of the D-domains of MKK7/9 in regulating the subcellular localization of these kinases.
RNA domain swapping typically demonstrates conservation of the native function of the domain in a non-native context.
Mapping the acetyl sites to specific domains of proteins allows for further understanding of how these acetyl marks affect the function of the domain within the protein, and how modification of different sites within the same protein can lead to diverse outcomes.
