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These results demonstrate that TDRD3 can enhance the biochemical activities of Top3β on both DNA and RNA substrates, in addition to its function of targeting Top3β to critical sites in subcellular compartments.
These results demonstrate that the streptavidin-αK peptide complex closely resemble the localisation of endogenous Irgm1 and provides a valuable novel method to investigate the function of targeting motifs of proteins.
Overexpression studies in both in vivo and in vitro proved miR-26a increases anoikis sensitivity in HCC, consistent with its function of targeting ITGA5.
The aim of the present work was to develop an HDL drug delivery system resembling native spherical HDL particles with the function of targeting the drug, lovastatin, to foam cells on the atherosclerosis plaque.
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Figure 4 illustrates outage probability as a function of targeted capacity.
Here, we discuss the engineering of 'smart' nanoparticles that are based upon recombinant adenovirus (Ad) vectors and that combine multiple functions of targeting, imaging and drug delivery.
Very few papers were found that examined in any detail the functioning of targeting and budgeting accountability approaches.
Thus, we expect this method will be useful for elucidating the functions of targeted genes.
The second is of point target detectability, predicting the changes in the correct decision probability as function of point target reflectivity and sound speed error.
The interconnected modifications create multiple layer of regulation to fine tune the function of target protein and to determine the functional read-out.
These studies aim to track the movement and function of target transcription factors in live cells by various optical methods.
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