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The constitutive activity is expressed as basal cAMP formation as a function of receptor expression determined by FACS.
Interestingly, there appears to be no statistical difference in fiber size as a function of receptor expression (p = 0.225).
Basal cAMP formation as a function of receptor expression was analyzed according to Ballesteros et al [74] using the linear regression module of GraphPad Prism 4 for Windows.
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The impaired constrictor responsiveness of conduit vessels was agonist dependent, suggesting possible loss of receptor expression or function.
There was also no feedback regulation of receptor expression as a function of VEGF signaling: i.e., constant total (free + occupied) receptor densities were maintained by defining sR = kint·[R total].
Experiments that measure the effectiveness of drugs as a function of entry receptor expression levels would provide tests of our proposed explanation.
In this case, the ratio of σ2/σ1 was similar to the ratio of F2/F1 (two-proportion z test, α = 0.05, Fig. 3A). Figure 3B shows the relative fractions of viscoelastic-liquid and viscoelastic-solid aggregates in data sets of 16 20 aggregates, as a function of α5β1 receptor expression and soluble fibronectin concentration.
Using the expression for, combining it with the expression for and rearranging terms yielded as a function of the receptor expression level, : 11 By letting, we obtained from the above expression the concentration of the EI required to block the infection of by 50%:.
Disease-free survival (DFS) and overall survival (OS) were analyzed as functions of TRAIL receptor expression.
This could be due to the effect of cortisol on the developing brain; glucocorticoid exposure during the fetal period has organizational effects on the developing brain, including the modification of synaptogenesis, neurotransmitter function, and glucocorticoid receptor expression with long-term implications for structure and function [ 22].
Diabetes had a differential effect on the constrictor responses to different receptor agonists, with serotonin affected more than phenylephrine and PGF2α constriction unchanged, suggesting that there may be differentially altered expression or function of receptors.
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Justyna Jupowicz-Kozak
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