Sentence examples for function of protein expression from inspiring English sources

Quantitation of PLA signal intensity as a function of protein expression confirmed the importance of the hinge region for proximity ligation.

Hence, we sought to rule out the possibility that the differences observed were due to differences in expression levels between the different types of proteins regions by determining Pa/ Ps ratios as a function of protein expression levels (fig. 2 A).

These categories included oxidative metabolism and protein synthesis and modification, indicating that the expression levels of mRNA transcripts supporting these biological functions are more predictive of protein expression compared with other functional categories.

They function as negative posttranscriptional regulators of protein expression, by interacting with specific miRNA and their degradation.

This affinity-based molecular pull-down method, facilitated by epitope tagging of recombinant proteins, has enabled detailed investigation of protein expression, function and interaction patterns.

After germline transmission, both transgenes were bred to, and maintained at, homozygosity, suggesting that the sites of transgene integration were not perturbing essential gene function and that high levels of protein expression were non-toxic.

Loss of this function by mutations or down-regulation of protein expression has been linked to hypertrophic cardiomyopathy, arrhythmias, and progression of disease in failing hearts.

For a better understanding of cancers and their refined classification at the systems-level, the analysis of protein expression and function is of particular importance.

It has been known for many years that for a "normal" un-transformed cell to become immortal and subsequently tumorigenic requires multiple pro-oncogenic changes in the levels of protein expression and function.

For example, in S. cerevisiae, temperature-sensitive mutants allow inhibition of protein function and/or expression within minutes, whereas in human cells siRNA-mediated suppression of CBC leads to loss of protein expression over hours and days, which may lead to indirect effects being observed.

To investigate the effect of pressure/flow on the barrier function and protein expression of normal and senescent porcine aqueous humor plexus (AAP) cells, which are the porcine equivalent of human Schlemm's canal endothelial cells.AAP cells were grown for 2 weeks in physiological (5% O2) or hyperoxic conditions (40% O2) to model cell senescence.