Sentence examples for function of par from inspiring English sources

Using (20) and (24), the transfer function of PAR

Thus, while it cannot be used in this way to extract precise internuclear distances, determining the maximal cross-peak intensity as a function of PAR mixing time can put an upper limit on a specified contact.

By combining β-lap and FK866, we uncouple NAD+ and ATP depletion from the robust formation of PAR noted with β-lap alone, allowing us to define the function of PAR formation in β-lap-induced cell death.

This suggests that the PERV receptor function of PAR-1 containing serine 109 may be impaired.

Taken together, these results reveal the critical function of Par-1-mediated Baz phosphorylation in the function of the COC.

In rats, the phosphorylation by CK2 at the major site, S124, prevents caspase-mediated Par-4 cleavage (D123) and consequently impairs the proapoptotic function of Par-4.

aPC-bound EPCR neutralizes the proinflammatory function of PAR-1 signaling by maintaining interaction with activated PAR-1, thereby abrogating Gq signaling.

In their study, Alvarez and colleagues [ 6] show that downregulation of Par-4 is 'necessary and sufficient' for breast cancer recurrence, which further underscores the tumor-suppressor function of Par-4.

However, the already small number of hatching progeny in the wild-type background makes it difficult to draw a firm conclusion regarding a redundant function of par-3 or hmp-2 with the crumbs genes.

Since data on the role of PAR-1 in severe infection are sparse and the function of PAR-1 in bacterial pneumonia and sepsis to date is unknown, we here investigated the involvement of PAR-1 in the host response to pneumococcal pneumonia.

These so-called PAR-activating peptides (PAR-APs) have proved to be useful tools to study the function of PARs especially in settings in which more than one PAR subtype is expressed and stimulated by the same proteolytic enzyme [ 4, 23].