Sentence examples for function of niche from inspiring English sources

Furthermore, we looked for shared positions within species belonging to the same niche in order to explain diversifying evolution as function of niche pressures.

What are key steps in this evolution, and how does the form and function of the niche change as the niche matures?

Therefore, GSC self-renewal is controlled by coordinated functions of niche-initiated signaling pathways and intrinsic factors.

To maintain stemness, Lgr5+ stem cells require niche factors provided by surrounding cells such as nearby Paneth cells and myofibroblasts underneath the epithelial lining, and the function of these niche factors regulate diverse signaling pathways such as Wnt, BMP, and EGF (Crosnier et al., 2006).

An important function of the niche is to regulate precisely the balance between self-renewal and differentiation in order to maintain optimal organ function at all times.

Recent results provide evidence, that the supportive function of the niche is modified during the process of aging, thereby affecting the extrinsic mechanisms of stem cell control [25].

Studies on different model organisms indicate that the primary function of GSC niche signal is to prevent premature entry into meiosis/differentiation.

This 'nutritive' function of the niche remains a formal possibility, but in most systems few experimental data in support of it have so far emerged.

The main function of a niche probably is to provide specific factors necessary for the maintenance of the stem cell properties via a combination of intracellular and intercellular signalling.

The function of the niche in the intestinal crypt requires the presence of ECM molecules in the basement membrane and of humoral factors derived from mesenchymal stem cells and subepithelial myofibroblasts surrounding the epithelium and from epithelial cells proliferating within the crypt [173].

Therefore, one of the most important functions of the niche is its ability to regulate the balance between stem cell self renewal and quiescence [5].