Functional assessment of neurologic function is often not included.
Similar results were found when symptoms were grouped in categories defined a priori to reflect particular aspects of neurologic function, including affect, cognition, autonomic function, motor function, and vision (data not shown).
Performance Scales are a measure of handicap in twelve domains of neurologic function: mobility, hand function, vision, fatigue, cognition, bladder/bowel, sensory, spasticity, pain, depression, tremor/loss of coordination, and anxiety.
There were five components of neurologic function evaluated: level of consciousness, respiratory pattern, cranial nerve function, motor and sensory function, and behavior.
We assessed visual function using tests of near acuity, near visual contrast sensitivity (VCS; a sensitive indicator of neurologic function), and color discrimination.
Evaluation of neurologic function revealed cognitive impairment and increased learned helplessness, but not motor impairment following treatment with lopinavir/ritonavir.
Despite these challenges, properly designed clinical trials with validated endpoints will yield the most useful information on the neuroprotective effects of therapy, and may provide new treatment options to prevent the loss of neurologic function, including vision.
The results indicated that CSM was an effective therapeutic agent, that VCS was a sensitive and specific indicator of neurologic function, and that illness involved systemic and hypothalamic processes.
They could begin to be used as secondary outcomes so that more insight into the effects of different treatment strategies on a broader range of neurologic function can be acquired.
Helicopter aeromedical transport system is perceived to be safer than ground transport (GT) for the interfacility transfer of patients who have sustained spinal injury because of the concern for deterioration of neurologic function if there is a delay in reaching a higher level of care.
