Sentence examples for function of lineage from inspiring English sources
Added to this in Africa was the function of lineage expansion, one of the major purposes of slavery in the sub-Saharan region.
HES1 and DEC1 (Table 3) are immediate downstream targets of Notch signaling inhibiting the transcriptional expression and/or function of lineage-specifying genes involved in myogenesis [ 19].
In contrast to the generic targeting mechanisms employed by the KDM2 demethylases, the KDM6A and KDM6B enzymes appear to be actively guided to specific enhancers and promoters through the function of lineage-specific transcription factors that activate these genes [ 93, 95– 95].
Indeed, one striking observation corresponds to the high level of lineage-specific core genes of unknown function, which contrasts to HT-genes and highlights how little is known about the function of lineage-specific core genes in these archaea (fig. 7).
In order to address this issue, we used Vav-Cre mediated recombination to examine the impact of Runx1 loss of function on lineage priming in MPPs in the absence of Flt3-ITD.
61 In addition T-bet directly antagonizes the development of the Th2 and Th17 lineages, by suppressing the function of the lineage defining transcription factors GATA3 (GATA binding protein 3) and RORγt (retinoid acid receptor-related orphan receptor gamma t) respectively.
Enhancer landscapes are shaped by the integrated functions of lineage-specific and signal-dependent transcription factors.
As more genomes are sequenced opportunities for understanding evolutionary origins and functions of lineage-specific genes are increasing.
T cells show variable dependency on TCR signaling for homeostasis as a function of their lineage and differentiation state.
To investigate this, we evaluated the individual roles of Lck and Fyn in the development and function of γδ lineage cells.
Vav proteins are crucial for the development and function of hematopoietic lineage cells such as lymphocytes, neutrophils, natural killer cells, and osteoclasts [8] [16].
