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The results were found useful and with reduced toxicity of miRNA-145 inhibitor delivery to the lung by using the functionalized cationic lipopolyamine nanoparticles to recruit the pulmonary arteriopathy and rectify function of heart within rats with intense pulmonary arterial hypertension (PAH) [97].
Dr. Sonnenblick's findings about the structure and function of heart muscle cells and how the heart muscle contracts and relaxes contributed to the development by others of a new class of lifesaving drugs, called ACE inhibitors.
The onset of cardiac fibrosis post myocardial infarction greatly impairs the function of heart.
Indeed, β-blockers ameliorate the clinical condition and cardiac function of heart failure patients, but not exercise capacity.
In addition, recent studies have indicated that the structure and function of heart tissue are also sensitive to mechanical cues at the nano- and micro-scale.
It's noteworthy that the regenerative potential of adult heart is very low, and the limited recovery of morphology and function of heart following injury may be better referred as tissue repair.
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The objective of the present study is to compare cardiac function of hearts arrested and preserved with Celsior solution to hearts arrested with cardioplegia followed by preservation with UW solution.
The resulting loss of ATP perturbs ionic homeostasis and is accompanied by net loss of adenine nucleotides from the heart that is one cause of the reduced haemodynamic function of hearts (stunning) following ischaemia (Halestrap and Pasdois, 2009).
Hypertension has a serious harmful effect on the physiological and biochemical functions of heart that end with the appearance of cardio-vascular diseases.
The regimens of multiple-agent chemotherapy were determined individually by chemotherapy oncologists according to the functions of heart, liver, and kidney.
As intracellular Ca2+ is the key ion responsible for contractile functions of heart, we sought to evaluate the cardiomyocyte Ca2+ handling in response to aging.
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