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These results indicate the important function of guidance of Semaphorin-6A during the TC axons pathfinding at the embryonic and early postnatal stages.
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But the theories and methods for designing its flow path have been strictly confidential and the researches on the function of practical guidance have seldom been published.
Furthermore, it presupposed a main function of public guidance and management of processes, that turned out to be inappropriate in the enactment phase.
The diversity of function of these guidance molecules resides in their capacity to also function as co-receptors for VEGF enhancing its binding to VEGF receptors [ 19].
In other words, with the function of axon guidance Ephs/EPH could regulate the invasion, neoangiogenesis, and metastasis of gliomas [ 32, 33].
Our observation that unc-5 function can affect the guidance of neurons that primarily require unc-40 function for guidance is a similar to earlier observations that the loss of unc-40 function also affects guidance in neurons that primarily require unc-5 function (Hedgecock et al., 1990).
In the developing visual system, we are investigating the synaptic modulatory functions of axon guidance molecules, e.g. ephrins, Eph receptors, and Wnts, during the maturation of receptive field properties of visual neurons, after the completion of their axon guidance functions.
This study had shed light on novel functions of axon guidance molecules, and allowed us to address the complex interplay between molecular cues and electrical activities in the refinement of developing neural circuits.
Astrocytes have also been proposed to exert a wide range of functions including guidance of the development and migration of neurons during brain development, production of growth factors, maintenance of the integrity of the blood-brain barrier (BBB), and participating in the immune and repairing responses to disease and brain injury [ 12, 13].
Explaining the Fed's reaction function, as this sort of guidance is called, has always been a key function of Fedspeak.
A strong structure-activity relationship was observed as a function of AgNPs functionality; providing guidance to activity prediction and rational design of effective antimicrobial nanoparticles.
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