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Moreover, we derive the probability density function of gene duplication times for each mechanism.
In addition to increasing transcript abundance, another presumed function of gene duplication is to allow for the development of new protein functions [ 38].
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A common theme in the evolution of new functions consists of gene duplication followed by functional divergence.
Testing of these hypotheses will require further examination of gene function in the context of gene duplication patterns in species exhibiting various nodule characteristics across the legumes.
Second, we exploit the recent availability of a genome evolution simulation tool to assess the performance of BBH as a function of the rate of gene duplication.
Since phenotypic difference is likely to be caused by new genes and functions, and gene duplication is believed to be one of the major mechanisms for organisms to generate new genes and functions [11], the dynamics of gene duplication can be a good feature for genome-wide comparisons between species.
Much of the innovation in biological function has been attributed to events of gene duplication.
To test these hypotheses, I estimated the impact of gene duplication and metabolic function upon intraspecific gene expression variation of segmental and tandem duplicated genes within Arabidopsis thaliana.
Co-option of new paralogues into novel functions (neofunctionalisation) is a common outcome of gene duplication events [ 47] and may underlie adaptations to specific ecological niches [ 48- 51].
This is ultimately a story of gene duplication, changes in function and changes in the area in which particular genes are expressed.
Our results point to a large contribution of gene duplication to mitochondrial functions during spermatogenesis and to strong selective forces (revealed by particular tendencies) underlying the origin and evolution of these genes.
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