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Further characterization of the function of conserved domains within the tail suggests that RNA transport activity relies on the AMB site.
Hence, a possibly function of conserved elements outside of exons, repetitive elements, or CpG island promoters might be regulatory enhancer or silencer functions.
The epithelium of C. elegans is a valuable model system for exploring the function of conserved genes involved in epithelial development (Kagoshima and Shigesada, 2007; Joshi et al., 2010).
Central to all of these processes is the assembly and function of conserved SUN KASH bridges, or LINC complexes, that span the nuclear envelope.
Before evaluating the regulatory function of conserved blocks in the tephritid eve locus, we examined the endogenous expression patterns of eve in C. capitata embryos.
One possible function of conserved DNA sequence elements is to facilitate DNA recombination.
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Functions of conserved miRNA target genes, as a group, are less diverse than functions for non-conserved miRNA target genes (only validated or high-confidence targets were compared).
Based on these and other considerations, Nematostella is considered an attractive model to capture the ancient functions of conserved genes and signalling pathways among the Metazoa.
The functions of conserved long AARs are summarized.
To get insight into or predict the functions of conserved and new miRNAs, a miRNA target search was performed to identify their putative targets (see Methods).
However, the function of these conserved sequences as HLA-restricted T cell epitopes and the incidence of variant sequences in association with the conserved sequences were not known.
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