Exact(4)
Although the anti-apoptotic function of BIS appears to largely contribute to tumor expansion and resistance to chemotherapy, the impact of BIS on the inhibition of senescence and subsequent tumor progression has not been elucidated.
The regulatory function of BIS on STAT3 solubility is in line with previous findings indicating that BIS participates in PQC process to prevent the accumulation of misfolded proteins.
Altogether, these data strongly indicate that loss of the dis-aggregating function of BIS and/or 14-3-3 14-3-3 14-3-3ble for STAT3 aggregation, which leads to the functional inactivation of STAT3.
Considering that little is known about the regulatory mechanism of p27-mediated senescence induction, our results describe a novel function of BIS, extending from anti-apoptotic or anti-stress roles to the negative regulator of p27-mediated senescence.
Similar(56)
Figure 3 Bandgap energy of InPBi measured from absorption spectra as a function of Bi composition.
The use of Varshni's law, bandgap at 0 K, thermal expansion coefficient, and Debye temperature was determined as a function of Bi composition.
R-curves for layered media are predicted as a function of bi-layer thickness, volume fraction, density of flaw sites, and inhomogeneity in fracture toughness and elastic modulus.
In this work, the parameters of bi-kappa distribution are set to σ = 20, k = 1. Figure 2 Probability distribution function of bi-kappa noise for different values of parameters.
This study evaluates how the principal function of bi-directional electric meters affects the monitored amount of self-consumed and produced excess electricity for dwelling buildings connected to the grid by three phases.
To understand the function of BI-1 in vivo, we investigated bleomycin-induced fibrosis in BI-1 knockout mice.
For comparison, the critical values for the static instability (Pd, Equation (27); Qd, Equation (28)), which might be related to modal voice production [2] as discussed in Section 2.5, are also shown in Figures 5 and 6 as functions of bi.
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