Sentence examples for function of activating from inspiring English sources

The variation in antagonist potency as a function of activating ligand might arise for a number of different reasons.

We have identified the mechanism of this longer half-life of NF-κB in chromosome instability as the function of activating transcription factor (ATF -3.

A likely explanation for the inability of transfected TFs to generate myelin-expressing cells was the possible existence of a repressive histone code that would counteract the function of activating TFs.

In conclusion, mice deficient regarding the function of activating FcγRs respond to an Hg-induced autoimmune stimulus with increased levels and altered quality of CIC compared with mice expressing the intact receptors.

Signals induced by these ligand-receptor interactions serve the function of activating or inducing cell death by apoptosis.

As a result, tumorigenic cells paradoxically often lose the function of activating alternative cascades that normally act in parallel.

Mutation of ALK at position 1174 F1174II) generates a gain-of-function receptor capable of activating intracellular targets such as ERK (extracellular signal regulated kinase) and STAT3 (signal transducer and activator of transcription 3) in a ligand-independent manner.

PC9 cells harbor a gain-of-function activating mutant of EGFR [ 10], which suggests the facilitating role of ARNO on ERBB signaling is not limited to wild-type receptors.

We therefore examined the function of genes activated by TNF in hSAECs but not activated after EMT, and those activated after EMT but not in hSAECs.

The reciprocal developmental functions of activating and inactivating deiodinases explain why D3 knockout mice exhibit growth restriction, neonatal mortality, and abnormal thyroid status (4).

Regulation of DCs maturation occurs through the function of Janus activated kinase (JAK /signal transducer and activator of transcription (STAT) signaling pathway [3].