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Limitations associated with tendon displacement measurement and clamping, and uncertainties as to whether in vitro material represents intact tendon function necessitate measuring hysteresis under in vivo conditions.
Limitations associated with displacement measurements and clamping, and uncertainties as to whether in vitro testing represents physiological function, necessitate developing a method for assessing the mechanical properties of tendinous tissue in the in vivo state.
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The importance of electrostatic interactions for enzyme function necessitates methodologies that are capable of monitoring local changes in electrostatics in conjunction with catalysis.
Podocyte effacement results in proteinuria, progressive renal damage with glomerular scarring, and eventual loss of renal function, necessitating renal replacement therapy in humans.
At this point in the silent process, there are few opportunities to prevent malignant outcomes, 19 such as further declines in bone strength and renal function necessitating hemodialysis.
Cell function necessitates the assemblage of proteins into complexes, a process which requires further regulation on top of the fairly understood mechanisms used to control the transcription and translation of a single protein.
As described in the study with rapamycin and Akt inhibitor, GSK690693, inhibition of the mTOR pathway may increase insulin resistance and possibly reduce β-cell function, necessitating vigilant glucose monitoring and active intervention to control hyperglycaemia (El-Salem et al, 2007; Crouthamel et al, 2009).
These various functions necessitate unique RNA structures that are specialized for each particular task and often require RNA to interact with other molecules in the cell, such as metal ions, proteins, small metabolites, and other nucleic acids.
The differences between their physiological functions necessitate the need for keeping both genes in non-mammalian vertebrates.
As these proteins could be involved in ruminant strain host tropism, their functions necessitate further exploration.
Undoubtedly, the role of emotion-focused coping in manifestations of general health and physical functioning necessitates further demonstration.
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