Sentence examples for function mouse from inspiring English sources

Both gain of function and loss of function mouse models for understanding gonadotropin action in a whole animal context have already been generated.

To further investigate TIMP-3 function, mouse HSC were retrovirally transduced with human TIMP-3 and transplanted into lethally irradiated recipients.

To examine the in vivo developmental and physiological roles of ING2, with particular interest to testicular development and function, mouse Ing2 gene was knocked out using a Cre-loxP recombination system (Fig. S2A).

Human autosomal dominant, gain of function mutations and a loss of function mouse knockout both caused focal and segmental glomerulosclerosis but no systemic tumorigenicity has been observed [46], [47], suggesting that α-actinin-4 variation per se may not be oncogenic.

Besides Nkx2.5, Slc40a1 and Bmi1 were activated by wildtype Bapx1 and the loss-of function mouse mutants of these genes exhibit a hypoplastic spleen phenotype.

In the present study, we have generated a "gain of function" mouse model to further understand the in vivo roles of Gasp1.

Of course, the navy often took them on ships, but there they performed a function, mousing for the officers.

To evaluate its role in neural function, mice have been generated lacking this enzyme.

β-catenin loss of function mice had the genotype β-cateninfloxedexon3−6/floxedexon3−6 β-cateninfloxedexon3−6/floxedexon3−6

Before assessment of cardiac function, mice were allowed to stabilize for at least 10 minutes.

HDAC4-null mice display ectopic and premature mineralization of endochondral bones, mimicking the Runx2 gain of function mice [ 14].