Sentence examples for function leading from inspiring English sources

Nonetheless, the Asp390Gly mutation leads to loss of function leading the pathological condition.

Second, duplicate genes can diverge in function, leading to greater functional diversity inside the genome [ 15].

In the setting of ALF, astrocyte swelling/injury leads to astrocyte dysfunction and consequently impairs neuronal function leading to HE.

Methylation effectively disables the gene's function, leading to reduced levels of Treg cells.

Here, we show that RNR-α has a previously unrecognized DNA-replication inhibition function, leading to growth retardation.

Lower doses can alter cellular function, leading to an increased risk of cancer.

We report that SRF deletion disrupted epidermal barrier function leading to early postnatal lethality.

Accordingly, disruptions in this pathway affect placental development and function leading to altered fetal programming.

This may adversely affect islet viability and function leading to the observed failure of islet transplantation.

Alzheimer's disease (AD) is characterized by the progressive loss of cognitive function leading to dementia and by the accumulation of amyloid-beta (Aβ) in the brain1.

Yuan, P. et al. TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy.