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While our FMD findings suggest that endothelial-dependent function is unchanged during the early stages of recovery from exercise, the observation of two distinct types of acute responses suggest that the baseline state of the endothelium may influence the acute response to a bout of exercise.
This effect is now statistically significant, although the overall conclusion of our meta-analysis, that cyclophosphamide treatment did not result in clinically significant improvement of pulmonary function, is unchanged by this recalculation, as the improvement remains less than the predefined criterion of 10%.
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For either parity the physical observables, which depend on the square of the wave function, are unchanged.
Patients with improved renal function had a significant and independent increase in dialysis-free survival in comparison with patients whose function was unchanged and patients whose function was worsened after operation.
Both patients whose function was unchanged (P =.005; hazard ratio, 6.0; CI [2.2, 16.6]) and patients whose function was worsened (P =.03; hazard ratio, 2.2; CI [1.1, 4.5]) remained at increased risk of death or dialysis dependence.
With a change of 20% or more in EGFR being considered significant, 58% of patients had improved renal function, including 27 patients removed from dialysis dependence; function was unchanged in 35% and worsened in 7%.
Glucose and electrolytes levels were within normal values, as were urea and creatinine levels, suggesting kidney function was unchanged.
Myocardial diastolic function was unchanged.
The parameters of liver function were unchanged.
Vascular function was unchanged with intervention, without differences by gender or diagnosis.
Neurological function was unchanged for the next three days before signs of deterioration appeared.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com