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As macrophage function is suppressed, the proliferation and differentiation of muscle satellite cells are delayed in vivo; as a result, incomplete muscle regeneration and fibrosis occur (Segawa et al., 2008).
This further confirmed our above findings in the NK-function deficient mice that NK cell function is suppressed by Tregs.
Therefore, we tested the hypothesis that NK cell function is suppressed by Tregs in the setting of plasmid DNA vaccination.
Our results suggest that the impaired concentration of axon initial segment proteins is due to the lost of AIS microtubules specificity when HDAC6 function is suppressed.
Thus, Pol ε function is suppressed on the lagging strand, even when Pol δ is not present.
When cIAP1/cIAP2 expression or XIAP function is suppressed by IAP antagonist compound A (Supplementary Figure 1A), sensitivity to CD95L-mediated cell death is increased.
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In pinealectomized animals, thymus and spleen function were suppressed, as indicated by a decrease in the number of lymphocytes and neutrophils.
However, only Candesartan-mediated protective role in improving cardiac function was suppressed by tail-vein injection of Smad7 siRNA.
In contrast, Dinges et al. [42] reported that NK cell activity was increased in healthy adults who were sleep deprived; however, leukocyte function was suppressed.
Using radiotelemetry to record electrocardiograms and to measure heart rate variability (HRV), a well-accepted readout for autonomic function, we determined that HRV and autonomic function were suppressed in WNV-infected hamsters.
Siah1 function was suppressed by siRNA in MCF-7 cells.
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