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In cardiac myocytes, we detected expression of at least 11 Klfs (Table 2), with regulation of several family members from each of the activator/repressor groups by ET-1 (Fig. 1), suggesting that (at least in this system) neither tissue specificity nor classification according to global function is responsible for functional differences between individual Klfs.
The desirability function is responsible for modeling the multi-response statistical problem, the simulation approach generates required input data from a simulated system, and finally the genetic algorithm tries to optimize the model.
This supports our conclusion that some Lyn-specific function is responsible for downstream signaling in response to 3-IB-PP1 in IFN-γ primed cells.
This function is responsible for reading the superblock from the disk, initializing its internal variables, and returning a mounted filesystem descriptor to the VFS.
To verify that loss of JMJ13 function is responsible for the early flowering phenotype of jmj13, we transformed jmj13 with a 7.0 kb genomic construct (gJMJ13) including 2.6 kb upstream and 0.5 kb downstream of the coding region.
Ezh1-deficient mutant fish are viable and fertile, but the loss of ezh1 function is responsible for the earlier death of ezh2 mutant larvae indicating that ezh1 contributes to zebrafish development in absence of zygotic ezh2 gene function.
Similar(14)
Moreover, because no difference in liver enzymes between these subgroups was found, it is highly probable that alterations in hepatic flow rather than function were responsible for the low ICG-PDR.
The divergence in the ranking was maintained (Additional file 1: Table S1) showing that the scoring function was responsible for the divergence of the results, without excluding the role of the positioning algorithms (see the "Discussion" section).
Rather, we postulate that other MCMV genes that affect DC function are responsible for the absence of direct priming.
Mutations in the DDB2 gene leading to its loss of function are responsible for the phenotypic features of xeroderma pigmentosum group E (XP-E) patients, characterized by malignant skin tumors [14]-[16] [14]-[16]
Defects in membrane protein function are responsible for many debilitating and often fatal diseases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com