A large patient population who may benefit from advances in muscle regeneration are those undergoing total knee replacement (TKR), as quadriceps muscle function is recognised as paramount to subsequent rehabilitation and eventual outcome.
As a geriatric syndrome, therefore, the importance of overall neuromuscular function is recognised, with the recommendation that sarcopenia be defined as a combination of loss of physical performance as well as muscle mass [ 33].
The importance of cytoplasmic nanojunctions to cellular signaling and thus to the modulation of cell function was recognised several decades ago, henceforth the extent to which cellular nanospaces may contribute to the regulation of cell function received little attention.
The system is comprised of the Vasse and Wonnerup estuaries and provides habitat, at any one time of the year, for over 37,500 water birds comprising ~90 species, a function that is recognised by its designation as a Wetland of International Importance under the Ramsar Convention in 1990 (Lane et al. 2007).
Astrocyte pathology with altered expression of astrocyte-specific proteins essential for cerebral functioning and metabolism is recognised as a significant factor in AD and subject to intensive research [ 3, 48].
Most genetic defects generate mutated proteins that are degraded through the cell's quality control system; however, in many cases, conformational modifications do not affect the function of the protein, yet it is recognised as misfolded and prematurely degraded.
NGF is derived by proteolytic cleavage of a large precursor protein, proNGF, which is recognised to possess distinctive biological functions.
Hip osteoarthritis (OA) is recognised as a substantial source of disability, with pain and loss of function as principal symptoms.
Sealed with the red dot design award for 2009, the Edifier MP300 Plus is recognised for its high quality design and innovation in terms of form and function.
The role for androgens in vascular function has been recognised for several decades [42], [43] yet the cellular mechanisms remain rather elusive.
For humans, however, no obvious adaptive function has been recognised for entrainment, although it is obviously a key element in music performance and other group behaviours mentioned above.
