Altogether, these results imply that UNC93B1 interacts with STIM1 and that in 3d/3d DC STIM1 function is compromised.
The evidence does not suggest that drinking three to four litres of water a day is harmful, unless kidney function is compromised.
Promising results have also been reported in infants suffering from other lung disorders in which endogenous surfactant function is compromised.
Glomerular function is compromised in diabetic nephropathy (DN) by uncontrolled buildup of ECM, especially type IV collagen, which progressively occludes the capillaries.
Natural flood management is part of the solution, but so is enhanced channel management, which will occasionally require removing silt from channels where their flood defence function is compromised.
Conclusions: Pulmonary function is compromised by most lesions of the spinal cord, even in those with paraplegia, and is affected relative to the level of lesion.
Albumin extravasation into the brain parenchyma, which often occurs when BBB function is compromised, emerges as a potential regulator, as exposure to albumin alone was sufficient to induce similar transcriptional changes and degradation of PNNs around PV+ interneurons.
Where mouth opening is restricted to the extent that normal function is compromised, surgical treatment is often indicated [2, 3].
Most authors agree that after reconstruction of extensive proximal humeral lesions, the shoulder function is compromised [6].
If the pulmonary function is compromised or there is poor lung perfusion, the flatten-out phase will disappear.
These findings demonstrate a novel atheroprotective role for Ang-2 when endothelial cell function is compromised and suggest that growth factors, which stimulate NO release without inducing inflammation, could offer atheroprotection.
