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In some cases however, the duplicate is retained as functional gene and either a new function is acquired by one of the copies or the ancestral function is maintained or subdivided between the two copies [ 63].
Arnold (1994) distinguishes between "addition exaptations" in which a second function is acquired in addition to the initial function and "transfer exaptations" in which the shift to a new function involves the loss of the previous function.
Two major subsets of Foxp3+ Treg cells, natural and adaptive Treg cells, were defined based on whether their suppressor function is acquired during normal T cell development in the thymus or following TCR stimulation in peripheral tissues or in vitro [16], [17].
DLS measures the scattering intensity I q, t) of a sample's Brownian motion, and the autocorrelation function is acquired from G2 = 〈 I 0) I〉 = 1/ T∫ I t) I(t + τ) dt.
On the other hand, duplicated genes can be retained in the genome after neofunctionalization – when a completely new function is acquired [ 26] – or subfunctionalization – when either the two genes become specialized in different tissues or at different developmental stages [ 27] or when the ancestral gene had several functions and the duplicates become specialized for certain of these functions.
If post-duplication neofunctionalization of protein structure is to promote the persistence of both paralogs, amino acid changing nucleotide substitutions must occur in at least one paralog soon after duplication, and this should be followed by increased purifying selection once new function is acquired [ 1, 60].
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Each autocorrelation function was acquired for 10 s, and averaged for 10 measurements.
Numerous genes encoding conserved proteins of unknown function were acquired by brown rot strains during their divergence from sequevar 3 Moko strains.
It is known that not all members of this family can produce butyrate, raising the question of whether this function was acquired laterally or was ancestrally present and then lost in several lineages.
In conclusion, the quasispecies behaves functionally like an ecosystem, where different emergent functions are acquired by nonviable sequences and have particular and defined roles.
As the core part of the fuzzy neural network, both fuzzy inference rule base and parameters of membership functions are acquired and adapted with reinforcement learning method which can achieve a predefined goal by directly interacting with its uncertain environment and by properly utilizing past experience derived from previous actions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com