Sentence examples for function is abolished from inspiring English sources
These results suggest that although ASE neurons express most cell specific markers in the ceh-36 background [22], [25], [26], normal ASE function is abolished.
However, this is not an absolute rule as we did not detect morphological changes in eccrine sweat or tracheal submucosal glands, both of which are absent when Edar function is abolished.
This function is abolished via p53 degradation by the E6 protein of oncogenic HPV types or via cytoplasmic sequestration by complexing to mdm-2 protein [ 6].
The synthetase defect of the Arg217Cys mutation in human HCCS has been established previously; however, we determined that HCCS function is abolished with virtually any substitution of Arg217, suggesting that this residue is essential to HCCS activity/structure.
Instead, some information about the gene derives from experiments in rodents where AVPR1B function is abolished by either genetic manipulation or antagonist administration; these experiments imply the inherent difficulty in translating mouse phenotypes to humans, which is even more complicated in the case of genes involved in complex behavioral traits, as AVPR1B is suggested to be.
Even though the ligand-binding function was abolished by these two mutations, the expression of these mutants was normal at the protein level.
NFATc3 nuclear accumulation in pericytes was prevented when astrocytic function was abolished with the gliotoxin L-alpha-aminoadipate. Results suggest that astrocyte glutamate, via mGluR activation, may regulate gene transcription in pluripotent vascular pericytes [ 104].
Therefore, we concluded that p53-dependent functions are abolished in K8R hESCs after DNA damage.
Open image in new window Figure 4 p53-dependent functions are abolished in K8R hESCs and functions.
Open image in new window Figure 6 p53-dependent functions are abolished in K2R cells but increased in K6R cells.
We created double mutants with leo tK3, where leo and luc functions are abolished, and observed that the residual striped pattern is lost in all three cases.
