Sentence examples for function instability from inspiring English sources

Phosphorylation is thought to cause loss of tau function, instability of the microtubule, formation of NFTs, and neurodegeneration [ 84, 85].

Further, although loss of function instability phenotypes have been demonstrated for many of the genes in model systems, we observed enhanced expression of most genes in tumors, indicating that over expression, rather than deficiency underlies instability.

Contrary to expectation, we observed that greater chromosomal instability in breast tumors is associated with increased expression levels of many of these genes, even though they have loss of function instability phenotypes.

Such in vitro studies have generally assessed the consequences of functional deficiency one gene at a time and have found that individually many genes have loss of function instability phenotypes.

Alcohol contributes to the "geriatric giants", the four main health conditions that affect older people, they add, namely loss of cognitive function, immobility, instability and incontinence.

The ability of surgery to reverse the natural history of this problem suggests that restoring the capsulolabral complex back to its anatomical position can lead to normal function without instability.

Orthostathism may result in deteriorating cognitive function, gait instability, fatigue and generalized weakness [ 29].

Certain mutant pVHLs retain ability to regulate HIFs but lose their function by instability.

The two mutations associated with NCS we describe delete the sixth WDR73 C-terminal WD repeat domain and significantly alter the fifth, leading to loss of function, protein instability, and enhanced interactions with α- and β-tubulin.

Finally, a mutant sarcoglycan protein might fold and form a tetramer, exit the ER and reach the cell membrane, where it could cause loss of function or instability of the entire sarcoglycan complex.

One of the major reasons for inserting damping into bearings is that rotating machines are often requested in critical functioning conditions having sometimes to function under dynamic instability or close to critical speeds.