Sentence examples for function in tumor cells from inspiring English sources

Thus, the development of anti-MDM2 therapies may restore normal p53 function in tumor cells and induce growth suppression and apoptosis.

However, despite the multiple proteins and pathways known to be affected by cell adhesion molecules in general and ICAM-2 in particular, complete membrane-to actin linkages that regulate CAM function in tumor cells have been difficult to identify.

The presence of stem cell characteristics in glioma cells raises the possibility that mechanisms promoting the maintenance and self-renewal of tissue specific stem cells have a similar function in tumor cells.

Since blocking Stat3 function in tumor cells is also known to activate adaptive immunity [42], [43] it may be that IL-6 induced Stat3 is in part responsible for no/low activation of NK cells in the co-cultures of NK cells and either HEp2 cells or UCLA-1 or HOK-16B tumors.

Together, these findings suggest that the inappropriate production of the H3.5 mutant may compromise proper chromosomal function in tumor cells.

Compared to other MIR17HG family members, miR-18a is understudied and its function in tumor cells is largely undefined.

Additionally, studies have demonstrated the importance of VEGFR1 function in tumor cell survival.

The imine bond in Dex DOX stayed tough in neutral solution yet quickly fractured when pH was lowered, in which way DOX was locally released and functioned in tumor cells.

Through these domains, OPCML may bind directly to growth promoting or inhibitory molecules and modulate their functions in tumor cells.

We show that cells in high grade glioma co-express an array of markers defining neural stem cells (NSCs) and that these proteins can fulfill similar functions in tumor cells as in NSCs.

At present, much less is known about its expression and functions in tumor cells.