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It is thus not surprising that cilia and most ciliary genes are deeply conserved, both in structure and function, in the "tree of life".
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In the tree of functions the source of the function does not matter.
As the dual-EF-containing species are distantly related to each other, we propose that independent re-modelling of EF-1α function took place in multiple branches in the tree of eukaryotes.
The tree of functions, the tree of cells and the Tree of Life can hardly be one same thing.
Our functional phylogenomics analysis provided a quantitative test of these hypotheses for a large number of cellular functions in the phylogenetic tree of all sequenced prokaryotic genomes in GenBank.
The tree of functions is certainly not the tree of cells.
Curators can manually block propagation to descendants either by annotating a loss of the function at some point in the tree (loss of function is discussed below), or by removing a clade of sequences from the tree ('pruning'pruning
We propose that the re-modeling of the original EF-1α functions seemingly occurred in several independent branches of the tree of eukaryotes.
In its new job, the pole, the representation of the tree of life, rooted in the ground and reaching up toward heaven, serves exactly its original symbolic function: the unification of the earth and the sky.
Continued to infinity, this tree is called the tree of two successor functions (namely left successor and right successor).
Our other work focuses on reconstructing a large portion of the tree of cells, and hints of the tree of function can be seen in it (in preparation).
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