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SLC11A1 gene has a vital function in the pathway of macrophage activation [20].
Whilst progress in understanding the molecular basis of ovary development has been slower, several genes have now been demonstrated to function in the pathway of testis development, many of these comprising transcription factors or secreted signalling molecules expressed in a male-specific fashion during gonad development (reviewed in [5], [6]).
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UIMs are therefore particularly prevalent in proteins that function in the pathways of endocytosis and vacuolar protein sorting [32].
UIM motifs are also prevalent in the proteins that function in the pathways of endocytosis and vacuolar protein sorting, like Epsins [4], Eps15 [6], [6] and Hrs (yeast Vps27p) [8], [8], and in the DNA repair pathway, like RAP80 [9].
The observation that isoprene is still emitted while the expression of the gene was depleted is easily explained by its function in the pathway downstream of IDP biosynthesis.
Broad sensitivities to different DNA damage reagents suggest that these genes function in the universal pathway of DDR, for example, in the conserved ATM/ATR pathway [ 2].
The role of spontaneous retinal activity before eye opening in the maturation of form and function in the retinogeniculate pathway of the ferret.
Cytochrome c has a function in the intrinsic pathway of apoptosis and leads to the activation of caspase-3, which is a downstream enzyme in the apoptosis process and is involved in the execution phase of the death pathway [ 40].
These results are consistent with our view that CAF-1 and STI function in the same pathway of trichome differentiation.
This is not unexpected since other genes that function in the linear pathway of Rad23/Dsk2 target may also induce toxicity in rad23 dsk2 mutant cells upon their overexpression.
We conclude that RecJ and RecQ function in the same pathway of hyper-TLD in Δ uvrD cells, and the greater RecJ effect indicates a possible additional RecQ-independent role of RecJ.
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