Sentence examples for function in the niche from inspiring English sources

We examined the role of the heparin-binding growth factor pleiotrophin (PTN) in regulating HSC function in the niche.

To link Ubc9 function in the niche to overproliferation, we examined Ubc9−, Antp>Ubc9 wt progeny.

Extracellular matrix, in the form of three-dimensional spatial structures called fractones, plays also an important role in the niche functioning.

The purpose of this study was to establish an in vitro model for Mk function in the bone niche environment.

Collectively, these studies reveal the structure of a dynamic molecular machine that evolved to function in the human gastric niche.

Doak, G. R., Schwertfeger, K. L. & Wood, D. K. Distant relations: macrophage functions in the metastatic niche.

Transport functions in the renal niche related to tunneling nanotubes were not under analysis up to date.

The function of the niche in the intestinal crypt requires the presence of ECM molecules in the basement membrane and of humoral factors derived from mesenchymal stem cells and subepithelial myofibroblasts surrounding the epithelium and from epithelial cells proliferating within the crypt [173].

To grasp the nature of niche components in the mouse brain, we need to understand the major characteristics and functions of each element in the niche, to comprehend what role each cellular member plays in the procedure of NSCs maintenance, proliferation, and differentiation.

What are key steps in this evolution, and how does the form and function of the niche change as the niche matures?

The expression of PECAM-1 on HSCs and the bone marrow vasculature, together with the well established role for PECAM-1 in regulating cell adhesion, migration and activation in cells of haematopoietic origin prompted us to examine whether PECAM-1 could regulate HSC function in the bone marrow vascular niche.