Sentence examples for function in the human genome from inspiring English sources

In this study we use computational methods to identify new proteins (genes) and domains within proteins, with CM-related function in the human genome.

Supporting evidence is found in the fact that multispecies HSBs (msHSBs) involving nine mammals plus chicken, unlike EBRs, are enriched in gene ontology (GO) terms for organismal development, central nervous system, and brain function in the human genome.

Bioinformatics analyses predict that the majority of human genes undergo alternative splicing, suggesting that alternative splicing is a significant component in generating diversity of function in the human genome [ 11].

This study represents the first comprehensive study of MSRs in different human populations by applying novel statistical methods and identifies commonalities and differences in their organization and function in the human genome.

The columns contain functionally related gene sets (Feature), the enrichment significance of genes found in 225 candidate genes containing known functionally related genes (FDR), number of related genes found in 225 candidate genes (Genes in network), and the overall total number of genes associated with a particular function in the human genome.

Overall, this report presents some exciting new findings that are very timely in view of (i) extensive ChIPseq data in the literature demonstrating the localization of components of the Pol III transcription machinery adjacent to Pol II-transcribed genes and (ii) the widespread localization of SINE elements (of unknown function) in the human genome and near promoters.

This example highlights the challenges associated with finding novel gene functions in the human genome using established methods from the bacterial world.

This work highlights that finding gene candidates for metabolic functions in the human genome is not a trivial issue and the extensive manual effort to curate the computational predictions of candidate reactions highlight the overall quality and quantity of data included in Recon 1.

Neurexin-1, one of the largest genes in the human genome, is thought to function in cell adhesion, as well as synapse development and maintenance (Kirov et al. 2008, 2009).

However, the PWWP domain in association with the VHS-ENTH-ANTH domains found in the land plants, but not algae, and of the PWWP domain in association with the GLYR1 function found in the human genome, but not in the cnidarian or the choanoflagellate, may represent novel occurrences in the plant or metazoan lineages, respectively.

This assumption is supported by a recent systematic review of loss-of-function variants in the human genome, which found loss-of-function variants to consistently occur at lower frequencies [ 41].