Sentence examples for function in the fat body from inspiring English sources

In contrast, while disruption of CREB function in the fat body also reduced glycogen levels, it increased lipid stores, and did not affect starvation sensitivity (Figure 2 3).

In larvae, the amino acid transporter Slimfast and TOR function in the fat body as nutrient sensors to coordinate systemic growth (Colombani et al., 2003).

Mef2 sites are also associated with genes encoding key enzymes of anabolism, and Mef2 is required for normal expression of these genes; consequently, flies lacking Mef2 function in the fat body exhibit striking reductions in the total levels of triglyceride and glycogen.

Interestingly, flies with disruption of CREB functions in the fat body shows an obese-like phenotype.

One possibility is that CREB activity in the fat body regulates multiple aspects of glucose/glycogen metabolism in addition to the AKH/AKHR-mediated pathway, and that blocking all CREB functions in the fat body reduces total glycogen levels as a net effect.

To determine whether shrub functions cell-autonomously in the fat body, we expressed a dominant-negative Shrub GFP (Sweeney et al., 2006) using fat body-specific drivers (see Materials and Methods).

A group of specialized cells, referred to as oenocytes, can function as hepatocytes by mobilizing stored lipids in the fat body during periods of food deprivation (Gutierrez et al., 2007).

We show that Mef2 is required in the fat body for anabolic function and the immune response.

However, the combination of fat body-specific serp knockdown with reduced gene dose resulted in abnormally elongated tube (Fig. 4B,D,F), suggesting that Serp expressed in the fat body and trachea functions redundantly, and that fat body-derived Serp is only essential for tube morphogenesis when the trachea-derived product is limiting.

These results were confirmed by knocking down dFoxO expression in the fat body, indicating that dFoxO function is autonomously required in fat cells for the induction of DILP6.

The biochemical function of Fit is not known, but fit is highly expressed in the fat body [ 39].