Sentence examples for function in lymphocyte from inspiring English sources

Chen, J., Lansford, R., Stewart, V., Young, F. & Alt, F. W. RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.

Members of the mucolipin (TRPML) family of cation channels have been implicated in regulated vesicular transport in several tissues, but a role for TRPML function in lymphocyte vesicular transport physiology has not been previously described.

New insights into E-protein function in lymphocyte development.

Several recent reviews have provided a comprehensive discussion of biochemical, cellular, and genetic research on E2A function in lymphocyte development (1,2).

E proteins are essential at multiple stages of αβ T cell development and function in lymphocyte survival, proliferation and differentiation.

The small GTPase Ras-related protein 1 (Rap1) belongs to the Ras superfamily and has a pivotal function in lymphocyte integrin activation [9] [11].

Septin 7 function in lymphocytes, however, is poorly characterized.

Moreover, investigations on life-threatening DOCK8-deficiency in humans have pointed to a crucial role of DOCK8 in the immune system, since the loss of DOCK8 function in lymphocytes leads to impaired immunity and an increased disposition for recurrent infections29.

It also discusses theoretical considerations and technical approaches for engineering chimeric receptors in addition to experimental methods for analyzing their surface expression and function in lymphocytes.

Despite this, functions mediated by T and B cells were either absent or very minimal in all three, including cell-mediated responses in vivo; the in vitro proliferative response to mitogens, allogeneic cells, or antigens; effector cell function in lymphocyte-antibody lymphocytolytic interaction assays; and in vitro synthesis of IgG, IgA, and IgM.

In addition, these results indicate that there may be a change in PKC function in lymphocytes with aging.