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With this, AKAP13 plays a key function in enabling PKA-induced ERα phosphorylation and is causally involved in ERαS305P-mediated tamoxifen resistance.
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The Or83b gene class, an unusual member of olfactory receptor family, plays a critical role in enabling the function of conventional olfactory receptors.
GRFs are multifunctional and essential for viability, consistent with their role in enabling the function of numerous other TFs and/or in chromatin opening at numerous promoters (Badis et al. 2008), presumably including those of other essential genes.
To do that, Quora has built out a custom keyboard that has rich formatting functions built in, enabling users to easily add images, bullets points, or rich text into their answers.
As new business models emerge, the IT function is pivotal in enabling new revenue streams by driving change for competitive advantage.
These data support integrin α5 delivery to the plasma membrane as a key function of Rab21 in enabling CAF-promoted SCC invasion.
The function of GRFs in enabling the activity of sites for other TFs (e.g., Brandl and Struhl 1990) also represents a cooperative interaction, since the impact of the two sites (that of the GRF and that of the activating TF) on transcription is different from that of the sum of either site alone.
Thus, these two functions are helpful in enabling the quantification of particle coagulation.
For example, our transcriptomic data identifies many P. pacificus specific genes as upregulated in the dauer stage, which implies a potential function in adaptations enabling survival on beetles.
Previously described loss-of-function mutations in enabled are embryo lethal, and since one copy of the null alleles display no clear defects, it is highly unlikely that this gene would have been associated to a progressive adult phenotype in the course of a traditional loss-of-function screen.
Our ability to move beyond descriptions of single molecules and their functions reflects parallel evolution in enabling platform technologies and quantitative modeling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com