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Gene modification of stem cells prior to their transplantation enhances their survival and increases their function in cell therapy.
Our data support a pRb function in cell adhesion while elucidating the mechanism for this function.
These results suggest that APP antagonistically regulates APP-BP1's function in cell cycle progression.
Its function in cell death signaling is still an enigma [64].
In flies and vertebrates, β-catenin/Armadillo has a dual function in cell adhesion and transcriptional regulation [45].
Specific amino acids such as glutamine have been shown to enhance barrier function in cell culture or animal models [13].
In addition to its function in cell adhesion, β-catenin is a central player in the Wnt pathway [20] [22].
We have demonstrated that RAE-1 also exerts a non-immune function in cell proliferation of NSPCs [11].
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Indeed, mutations within this region in Cifs leads to loss of function in cell-based assays (Oswald, unpublished results, [14]).
Catenins link the transmembrane protein cadherin to the cytoskeleton and thus function in cell-cell adhesion.
Integrins are heterodimeric transmembrane proteins that function in cell-matrix and cell-cell adhesion.
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