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Thus, to compare its function in amphioxus to that in vertebrates, subcellular localization analysis was conducted.
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However, the p38 MAP kinase gene has not been identified in amphioxus to date.
However, the ASPP homologous gene has not been identified in amphioxus to date.
Although the function of vertebrate Dgat1 in the hepatic control of retinoid homeostasis has been questioned (Batten et al. 2004), in the absence of a clear amphioxus Lrat ortholog, the contribution of Dgat1 enzymes in amphioxus to the esterification of retinol for retinyl ester storage deserves further investigation.
This mechanism, which may function in amphioxus as well, represents another way to achieve the robustness of Bmp gradient [52].
Furthermore, Twist1/2 and Alx3/4 mark lateral plate mesoderm in vertebrates, indicating their function in amphioxus pharyngeal mesoderm is not necessarily skeletogenic.
A survey of the B. floridae genome identified 107 genes encoding SDR enzymes belonging to these families and, hence, with putative functions in amphioxus retinoid or steroid metabolism.
The distinct expression patterns of caspases may suggest their diverse functions in amphioxus immunity or other roles.
Our phylogenetic data indicate that this prereceptor regulation is also functioning in amphioxus and was hence already present in the last common ancestor of amphioxus and vertebrates.
To seek evidence of a primitive adaptive immune system (AIS) before vertebrate, we examined whether lymphocytes or lymphocyte-like cells and the related molecules participating in the lymphocyte function existed in amphioxus.
This may suggest that parts of the gut functions found in vertebrates are missing or are regulated differently in amphioxus compared to vertebrates.
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