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Importantly, 11β-HSD2 is not always colocalised with MR and so its function has expanded beyond involvement in electrolyte transport to include regulation of corticosteroid action.
More recently, the capping function has expanded to include the concept of protecting telomeres from checkpoints as loss of a single telomere elicits a Rad9p-dependent cell cycle arrest (Sandell and Zakian 1993).
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Their security function had expanded into the area of what we would consider to be private military operations, and they were being used almost as a mercenary force in conflict zones.
Since its discovery, our understanding of leptin's biological functions has expanded from antiobesity to broad effects on reproduction, hematopoiesis, angiogenesis, blood pressure, bone mass, lymphoid organ homeostasis, and T lymphocyte systems.
Additionally for some proteins, such as Mia40 and Tim17, functions have expanded in plants compared to those characterized in yeast.
Modelling efforts in P. falciparum focused on revealing indispensable metabolic functions have expanded the list of putatively essential genes and enzymes.
Key Points Modelling efforts in P. falciparum focused on revealing indispensable metabolic functions have expanded the list of putatively essential genes and enzymes.
The function of CAD has expanded as a tool to communicate and collaborate as well as to better control all phases of the architectural practices.
During metazoan evolution, the primary digestive function of phagosomes has expanded to include roles in development, tissue remodeling, apoptosis, and in innate and adaptive immunity [ 66].
Over the past decade the function of HO-1 has expanded from a heme-degrading enzyme to a key mediator of tissue protection and host defense, and its cytoprotective effects have been described in vivo and in vitro [ 24, 25, 28, 32- 42].
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